Publications & communications (sorted by type)
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Journals ▲
International journals (31)
31 | L. Gibart, H. Collavizza, J.-P. Comet. A Phenotypic Matrix for Greening Qualitative Regulatory Networks with Environments. BMC bioinformatics [accepted]. :, 2024. | ||
30 | F. Camilleri, J. Wenda, C. Pecoraro-Mercier, J.-P. Comet, D. Rouquié. Cell Painting and chemical structure read-across can complement each other for rat acute oral toxicity prediction in chemical early de-risking. Chemical Research in Toxicology. :, 2024. DOI doi.org/10.1021/acs.chemrestox.4c00169 | ||
29 | J.-P. Comet, H. Collavizza, L. Gibart. Constrained Kripke Structure for Identifying Parameters of Biological Models. Theoretical Computer Science [Available online 19 March 2024]. 996:114505, 2024. DOI https://doi.org/10.1016/j.tcs.2024.114505 | ||
28 | L. Gibart, R. Khoodeeram, G. Bernot, J.-P. Comet, J.-Y. Trosset. Regulation of Eukaryote Metabolism: An Abstract Model Explaining the Warburg/Crabtree Effect. Processes. 9:1496, 2021. DOI doi.org/10.3390/pr9091496 | ||
27 | I. Grenet, J.-P. Comet, F. Schorsch, N. Ryan, J. Wichard, D. Rouquié. Chemical in vitro bioactivity profiles are not informative about the long-term in vivo endocrine mediated toxicity. Computational Toxicology. 12:100098, 2019. DOI doi.org/10.1016/j.comtox.2019.100098 | ||
26 | I. Grenet, K. Merlo, J.-P. Comet, R. Tertiaux, D. Rouquié, F. Dayan. Stacked Generalization with Applicability Domain Outperforms simple QSAR on in vitro Toxicological Data. JCIM. 59(4):1486--1496, 2019. DOI doi.org/10.1021/acs.jcim.8b00553 | ||
25 | G. Bernot, J.-P. Comet, Z. Khalis, A. Richard, O.F. Roux. A Genetically Modified Hoare Logic. Theoretical Computer Science. 765:145-157, 2019. DOI 10.1016/j.tcs.2018.02.003, | ||
24 | I. Grenet, Y. Yin, J.-P. Comet. G-networks to predict the outcome of sensing of toxicity. Sensors. 18:3483, 2018. DOI 10.3390/s18103483, | ||
23 | J. Behaegel, J.-P. Comet, G. Bernot, E. Cornillon, F. Delaunay. A hybrid model of cell cycle in mammals. J. of Bioinformatics and Computational Biology. 14(1):1640001 [17 pp.], 2016. Preprint, DOI 10.1142/S0219720016400011, © [copyright World Scientific Publishing Company], http://www.worldscientific.com/worldscinet/jbcb. [Cf. Conferences Behaegel et al. 2015] | ||
22 | J.-P. Comet, A. Richard, J. Aracena, L. Calzone, J. Demongeot, M. Kaufman, A. Naldi, E.H. Snoussi, D. Thieffry. On circuit functionality in Boolean networks. Bulletin of Mathematical Biology. 75(6):906-919, 2013. DOI 10.1007/s11538-013-9829-2 | ||
21 | A. Richard, G. Rossignol, J.-P. Comet, G. Bernot, J. Guespin-Michel, A. Merieau. Boolean models of biosurfactants production in Pseudomonas fluorescens. PlosOne. 7(1):e24651, 2012. DOI 10.1371/journal.pone.0024651 | ||
20 | S. Taati, E. Formenti, J.-P. Comet, G. Bernot. On the impact of the distance between two genes on their interaction curve. Journal of Mathematical Biology. 64(1):131-147, 2012. [online First, february 16th, 2011], DOI 10.1007/s00285-010-0373-5 | ||
19 | M. Mabrouki, M. Aiguier, J.-P. Comet, P. Le Gall, A. Richard. Embedding of biological regulatory networks and properties preservation. Mathematics in Computer Science. 5(3):263-288, 2011. special issue | ||
18 | A. Richard, J.-P. Comet. Stable periodicities and negative circuits in differential systems. Journal of Mathematical Biology. 63(3):593-600, 2011. [online dec. 1st, 2010]. See also Erratum, 2015. | ||
17 | Z. Khalis, J.-P. Comet, A. Richard, G. Bernot. The SMBioNet Method for Discovering Models of Gene Regulatory Networks. Genes, Genomes and Genomics. 3(special issue 1):15-22, 2009. | ||
16 | S. Troncale, J.-P. Comet, G. Bernot. Enzymatic Competition: Modeling and Verification with Timed Hybrid Petri Nets. Pattern Recognition. 42(4):562-566, 2009. | ||
15 | M. Poudret, J.-P. Comet, P. Le Gall, F. Képès, A. Arnould, P. Meseure. Topology-based abstraction of complex biological systems: Application to the Golgi apparatus. Theory in Biosciences. 127:79-88, 2008. | ||
14 | J. Ahmad, O. Roux, G. Bernot, J.-P. Comet, A. Richard. Analysing formal models of genetic regulatory networks with delays: Applications to lambda phage and T-cell activation systems. Int. J. Bioinformatics Research and Applications. 4(3):240-262, 2008. | ||
13 | J. Ahmad, G. Bernot, J.-P. Comet, D. Lime, O. Roux. Hybrid modelling and dynamical analysis of gene regulatory networks with delays. ComPlexUs. 3(4):231-251 (Cover Date: November 2007), 2006. | ||
12 | S. Troncale, R. Thuret, C. Ben, N. Pollet, J.-P. Comet, G. Bernot. Modelling of the TH-dependent regulation of tadpole tail resorption. Journal of Biological Physics and Chemistry. 7(2):45-50, 2007. | ||
11 | A. Richard, J.-P. Comet. Necessary conditions for multistationarity in discrete dynamical systems. Discrete Applied Mathematics. 155(18):2403-2413, 2007. | ||
10 | D. Mateus, J.-P. Gallois, J.-P. Comet, P. Le Gall. Symbolic modeling of genetic regulatory networks. Journal of Bioinformatics and Computational Biology. 5(2B):627-640, 2007. | ||
9 | D. Filopon, A. Merieau, G. Bernot, J.-P. Comet, R. Leberre, B. Guery, B. Polack, J. Guespin-Michel. Epigenetic acquisition of inducibility of type III cytotoxicity in P. aeruginosa. BMC Bioinformatics. 7:272, 2006. | ||
8 | A. Richard, J.-P. Comet, G. Bernot. R. Thomas' modeling of biological regulatory networks: Introduction of singular states in the qualitative dynamics. Fundamenta informaticae. 65(4):373-392, 2005. | ||
7 | J. Guespin-Michel, G. Bernot, J.-P. Comet, A. Mérieau, A. Richard, C. Hulen, B. Polack. Epigenesis and dynamic similarity in two regulatory networks in pseudomonas aeruginosa. Acta Biotheoretica. 52(4):379-390, 2004. | ||
6 | G. Bernot, J.-P. Comet, A. Richard, J. Guespin. Application of Formal Methods to Biological Regulatory Networks: Extending Thomas' Asynchronous Logical Approach with Temporal Logic. J.T.B.. 229(3):339-347, 2004. | ||
5 | G. Mercier, N. Berthault, J. Mary, J. Peyre, A. Antoniadis, J.-P. Comet, A. Cornuéjols, C. Froidevaux, M. Dutreix. Biological detection of low radiation by combining results of two microarray analysis methods. Nucleic Acids Research. 32(1):e12, 2004. | ||
4 | J.-P. Comet. Application of Max-Plus algebra to biological sequence comparisons. Theoretical Computer Science. 293:189-217, 2003. | ||
3 | J.-P. Comet, J. Henry. Pairwise sequence alignment using a PROSITE pattern-derived similarity score. Computers & Chemistry. 26(5):421-436, 2002. | ||
2 | J.-N. Bacro, J.-P. Comet. Sequence alignment : an approximation law for the Z-value with applications to databank scanning. Computers & Chemistry. 25:401-410, 2001. | ||
1 | J.-P. Comet, J.-C. Aude, E. Glémet, A. Hénaut, J.-L. Risler, P.P. Slonimski, J.-J. Codani. Significance of Z-value statistic of Smith-Waterman Scores for Protein alignments. Computers & Chemistry. 23(3-4):317-331, 1999. Special issue |
National journals (2)
BioRXiv (1)
1 | F. Camilleri, J. Wenda, C. Pecoraro-Mercier, J.-P. Comet, D. Rouquié. Cell Painting morphological profiles can complement QSAR models for rat acute oral toxicity prediction. BioRXiv. 2024. |
Books chapters and editions ▲
Books chapters (18)
18 | H. Collavizza, G. Bernot, J.-P. Comet. Formal Verification Methods for Modeling in Biology: Biological Regulation Networks. In Symbolic Approaches to Modeling and Analysis of Biological Systems (eds. C. Lhoussaine, E. Remy). pp. 255--312, ISBN: 978-1-78945-029-3, DOI: 10.1002/9781394229086.ch8, ISTE, 2023. | ||
17 | H. Collavizza, G. Bernot, J.-P. Comet. Méthodes de vérification formelle pour la modélisation en biologie : le cas des réseaux de régulation biologique. In Approches symboliques de la modélisation et de l’analyse des systèmes biologiques (eds. C. Lhoussaine, E. Remy). pp. 275--335, ISBN: 9781789480290, DOI: 10.51926/ISTE.9029.ch8, ISTE, 2022. | ||
16 | E. Cornillon, J.-P. Comet, G. Bernot, G. Enée. Hybrid Gene Networks: a new Framework and a Software Environment. In Proc. of the Thematic Research School on Advances in Systems and Synthetic Biology, Modelling Complex Biological Systems in the Context of Genomics (eds. P. Amar, F. Képès, V. Norris). pp. 57-84, ISBN: 978-2-7598-1971-3, EDP Science, 2016. | ||
15 | B. Miraglio, G. Bernot, J.-P. Comet, C. Risso-de Faverney. Towards a Computer Aided Toxicology. In Proc. of the Thematic Research School on Advances in Systems and Synthetic Biology, Modelling Complex Biological Systems in the Context of Genomics (eds. P. Amar, F. Képès, V. Norris). pp. 85-101, ISBN: 978-2-7598-1971-3, EDP Science, 2016. | ||
14 | K.J.E. Carpio, G. Bernot, J.-P. Comet, F. Diener. Probabilistic Gene Network. In Proc. of the Thematic Research School on Advances in Systems and Synthetic Biology, Modelling Complex Biological Systems in the Context of Genomics (eds. P. Amar, F. Képès, V. Norris). pp. 77-90, EDP Science, 2015. | ||
13 | G. Bernot, J.-P. Comet, E.H. Snoussi. Formal methods applied to gene network modelling. In Logical Modeling of Biological Systems (eds. K. Inoue, L. Fariñas). pp. 245-289, ISBN 978-1-84821-680-8, ISTE & Wiley, 2014. | ||
12 | G. Bernot, J.-P. Comet, C. Risso-de Faverney. Regulatory networks. In Computational Toxicology (eds. B. Reisfeld, A. Mayeno). pp. Volume II, pp 215-234, ISBN 978-1-62703-058-8 (print) 978-1-62703-059-5 (online), DOI 10.1007/978-1-62703-059-5_9, 2013. | ||
11 | G. Bernot, J.-P. Comet, A. Richard, M. Chaves, J.-L. Gouzé, F. Dayan. Modeling and analysis of gene regulatory networks. In Modeling in Computational Biology and Biomedicine, A Multidisciplinary Endeavor (eds. F. Cazals, P. Kornprobst). pp. 47-80, ISBN 978-3-642-31208-3, Springer, 2013. | ||
10 | J.-P. Comet, G. Bernot, A. Das, F. Diener, C. Massot, A. Cessieux. Simplified models for the mammalian circadian clock. In Proc. of the Evry Spring school on Modelling complex biological systems in the context of genomics (eds. P. Amar, F. Képès, V. Norris). pp. 85-106, EDP Science. [Cf. Conférences 15], 2012. | ||
9 | J.-P. Comet, G. Bernot. Introducing continuous time in discrete models of gene regulatory networks. In Proc. of the Evry Spring school on Modelling complex biological systems in the context of genomics (eds. P. Amar, F. Képès, V. Norris). pp. 61-94, ISBN : 978-2-7598-0545-7, EDP Science, 2010. | ||
8 | Z. Khalis, G. Bernot, J.-P. Comet, Observability Group. Gene Regulatory Networks: Introduction of multiplexes into R. Thomas' modelling. In Proc. of the Nice Spring school on Modelling complex biological systems in the context of genomics (eds. P. Amar, F. Képès, V. Norris, G. Bernot). pp. 139-151, ISBN : 978-2-7598-0437-5, EDP Science, 2009. | ||
7 | M. Poudret, J.-P. Comet, P. Le Gall, F. Képès, A. Arnould, P. Meseure, J.-M. Verbavatz, A. Rambourg. Toward a computer-aided methodology for topology-based simulation of the Golgi apparatus. In Proc. of the Lille Spring school on Modelling complex biological systems in the context of genomics (eds. P. Amar, F. Képès, V. Norris, P. Tracqui). pp. 89-104, ISBN : 978-2-7598-0075-9, EDP Science, 2008. | ||
6 | D. Mateus, J.-P. Comet, J.-P. Gallois, P. Le Gall. Inferring parameters of genetic regulatory networks with symbolic formal methods. In Proc. of the Evry Spring school on Modelling complex biological systems in the context of genomics (eds. P. Amar, F. Képès, V. Norris, P. Tracqui). pp. 51-70, ISBN : 978-2-7598-0019-3, EDP Science, 2007. | ||
5 | A. Richard, J.-P. Comet, G. Bernot. Formal Methods for Modeling Biological Regulatory Networks. In Modern Formal Methods and Applications (eds. H.A. Gabbar). pp. 83-122, ISBN: 1-4020-4222-1, Springer, 2006. | ||
4 | J. Mary, G. Mercier, J.-P. Comet, A. Cornuéjols, C. Froidevaux, M. Dutreix. Utilisation d'une méthode de sélection d'attributs pour l'analyse du transcriptome de cellules de levures exposées à de faibles doses de radiation. In Informatique pour l'analyse du transcriptome (eds. J.-F. Boulicaut, O. Gandrillon). pp. 189-205, ISBN: 2-7462-0850-4, Hermes, 2004. | ||
3 | G. Bernot, J. Guespin-Michel, J.-P. Comet, P. Amar, A. Zemirline, F. Delaplace, P. Ballet, A. Richard. Modelling, observability and experiment: a case study. In Proc. of the Dieppe Spring school on Modelling and simulation of biological processes in the context of genomics (eds. P. Amar, F. Képès, V. Norris, P. Tracqui). pp. 49-55, ISBN : 2-84704-036-6, Publisher Frontier group, 2003. | ||
2 | J. Mary, G. Mercier, J.-P. Comet, A. Cornuéjols, C. Froidevaux, M. Dutreix. Using an attribute estimation technique for the analysis of microarray data. In Proc. of the Dieppe Spring school on Modelling and simulation of biological processes in the context of genomics (eds. P. Amar, F. Képès, V. Norris, P. Tracqui). pp. 69-77, ISBN : 2-84704-036-6, Publisher Frontier group, 2003. | ||
1 | J.-J. Codani, J.-P. Comet, J.-C. Aude, E. Glémet, A. Wozniak, J.-L. Risler, A. Hénaut, P.P. Slonimski. Automatic analysis of large scale pairwise alignments of protein sequences. In Methods in microbiology Vol. 28, Automation, Genomic and Functional Analysis pp. 229-244, Academic Press, 1999. |
Edition of a book (1)
1 | Modelling and simulation of biological processes in the context of genomics (eds. P. Amar, J.-P. Comet, F. Képès, V. Norris). ISBN : 2 84704 0374, Publisher Frontier group, 2004. |
Edition of a special issue of a national journal (1)
1 | Modélisation et simulation pour la post-génomique (eds. J.-P. Comet, M. Kaufman), numéro spécial de T.S.I., 26:1-2, [éditorial de 4 pages], 2007. |
Conferences and workshops ▲
Refereed international conferences and workshops - with proceedings (30)
30 | R. Michelucci, J.-P. Comet, D. Pallez. Comparing diverse planning strategies with continuous Monte Carlo Tree Search applied to hybrid Gene Regulatory Networks, ICTAI 2024 : The 36th IEEE International Conference on Tools with Artificial Intelligence. Herndon, VA, USA. 27-30 Oct. 2024, 2024. | ||
29 | G. Grataloup, D. Pallez, G. Bernot, J.-P. Comet. Single-objective constrained optimization for Gene Regulatory Networks Modeling, EA 2024 : Artificial Evolution. Bordeaux, France. 29-31 Oct. 2024, LNCS, 2024. | ||
28 | R. Michelucci, D. Pallez, T. Cazenave, and J.-P. Comet. Improving continuous Monte Carlo Tree Search for identifying parameters in hybrid Gene Regulatory Networks, 18th International Conference on Parallel Problem Solving From Nature PPSN. Hagenberg, Austria. Sept. 14-18, 2024. | ||
27 | R. Michelucci, V. Callegari, J.-P. Comet, D. Pallez. Cellular Genetic Algorithms for identifying variables in hybrid Gene Regulatory Networks, 27th European Conference, EvoApplications 2024, Held as Part of EvoStar . Aberystwyth, Wales, United Kingdom. 3-5 Apr.. vol. 14634 pp. 131-145, 2024. DOI doi.org/10.1007/978-3-031-56852-7_9. | ||
26 | H. Sun, J.-P. Comet, M. Folschette, M. Magnin. Condition for sustained oscillations in repressilator based on a hybrid modeling of gene regulatory networks, Bioinformatics 2023. Lisbon, Portugal. 16-18 Feb. 2023. vol. 12881 pp. 29-40, 2023. DOI doi.org/10.5220/0011614300003414. | ||
25 | R. Michelucci, J.-P. Comet, D. Pallez. Evolutionary continuous optimization of Hybrid Gene Regulatory Networks, EA 2022 : Artificial Evolution. Exeter, England. 31 Oct. 2022 - 2 Nov. 2022, LNCS, 2022. | ||
24 | L. Gibart, H. Collavizza, J.-P. Comet. Greening R. Thomas’ Framework with Environment Variables: a Divide and Conquer Approach, CMSB 2021 : 19th International Conference on Computational Methods in Systems Biology (CMSB). Bordeaux, France. 22-24 September, LNBI. vol. 12881 pp. 36-56, 2021. DOI doi.org/10.1007/978-3-030-85633-5_3. | ||
23 | L. Gibart, G. Bernot, H. Collavizza, J.-P. Comet. TotemBioNet Enrichment Methodology: Application to the Qualitative Regulatory Network of the Cell Metabolism, BIOINFORMATICS 2021 : 12th International Conference on Bioinformatics Models, Methods and Algorithms. online. 11-13 February, 2021. vol. 3 pp. 85-92, 2021. | ||
22 | D. Boyenval, G. Bernot, H. Collavizza, J.-P. Comet. What is a cell cycle checkpoint? The TotemBioNet answer, the 18th International Conference on Computational Methods in Systems Biology (CMSB). online. September 23-25, 2020, LNCS. vol. 12314 pp. 362-372, 2020. DOI doi.org/10.1007/978-3-030-60327-4_21. | ||
21 | J. Behaegel, J.-P. Comet, M. Pelleau. Identification of Dynamic Parameters for Gene Networks, the 30th IEEE International Conference on Tools with Artificial Intelligence (ICTAI). Volos, Greece. November 5-7, 2018 pp. 122-129, 2018. | ||
20 | I. Grenet, Y. Yin, J.-P. Comet, E. Gelenbe. Machine Learning to Predict Toxicity of Compounds, The 27th International Conference on Artificial Neural Networks (ICANN). Rhodes, Greece. 5-7 October 2018, LNCS. vol. 11139 pp. 335-345, 2018. | ||
19 | J. Behaegel, J.-P. Comet, M. Folschette. Constraint Identification Using Modified Hoare Logic on Hybrid Models of Gene Networks, International Symposium on Temporal Representation and Reasoning (TIME). Mons, Belgium. 16-18 October 2017 pp. 5:1--5:21, 2017. | ||
18 | B. Miraglio, G. Bernot, J.-P. Comet, C. Risso-de Faverney. Detecting Toxicity Pathways with a Formal Framework based on Equilibrium Changes, Computational Methods for Systems Biology (CMSB). Darmstadt, Germany. 27-29 September 2017, LNBI. vol. 10545 pp. 196-213, 2017. | ||
17 | B. Miraglio, G. Bernot, J.-P. Comet, C. Risso-de Faverney. A Qualitative Framework Dedicated to Toxicology, International Conference on Bioinformatics Models, Methods and Algorithms. Porto, Portugal. 21-23 february 2017, 2017. | ||
16 | J. Behaegel, J.-P. Comet, G. Bernot, E. Cornillon, F. Delaunay. A hybrid model of cell cycle in mammals, 6th International Conference on Computational Systems-Biology and Bioinformatics (CSBio'2015). Bangkok, Thailand. November 22-25, 2015, 2015. [Cf. Journals Behaegel et al. 2016]. | ||
15 | J.-P. Comet, G. Bernot, A. Das, F. Diener, C. Massot, A. Cessieux. Simplified models for the mammalian circadian clock, 3rd International Conference on Computational Systems-Biology and Bioinformatics (CSBio'2012). Bangkok, Thailand. October 3-5, 2012, Procedia Computer Science. vol. 11 pp. 127-138, 2012. [Cf. Chapters 11]. | ||
14 | J.-P. Comet, J. Fromentin, G. Bernot, O. Roux. A formal model for gene regulatory networks with time delays, 1st International Conference on Computational Systems-Biology and Bioinformatics (CSBio'2010). Bangkok, Thailand. November 3-5, 2010, CCIS. vol. 115 pp. 1-13, 2010. | ||
13 | G. Bernot, J.-P. Comet, E. Formenti, S. Taati. Gene regulatory networks: the impact of distance between genes, 19th International Symposium in Mathematical Theory of Networks and Systems, MTNS'2010. Budapest (Hungary). July 5-9, 2010, 2010. | ||
12 | G. Bernot, J.-P. Comet, Z. Khalis. Gene regulatory networks with multiplexes, European Simulation and Modelling Conference, ESM'2008. Le Havre (France). October 27-29, 2008, 2008. ISBN 978-90-77381-44-1, pp. 423-432, 2008. | ||
11 | M. Poudret, A. Arnould, J.-P. Comet, P. Le Gall. Graph Transformation for Topology Modelling, International Conference on Graph Transformation. Leicester (United Kingdom). September 7-13, 2008, LNCS. vol. 5214 pp. 147-161, 2008. | ||
10 | M. Mabrouki, M. Aiguier, J.-P. Comet, P. Le Gall. Property preservation along embedding of biological regulatory networks, Algebraic Biology. Austria. July 31st-August 2d, 2008, LNCS. vol. 5147 pp. 125-138, 2008. | ||
9 | S. Troncale, J.-P. Comet, G. Bernot. Verification of biological models with timed hybrid Petri nets, Proc. of the 2007 Intl Symp on Computational Models for Life Sciences (CMLS07). Gold Coast, Queensland, Australia. December 17-19 , 2007, American Institute of Physics Conference Proc Series (AIP). vol. 952 pp. 287-296, 2007. Pham, Tuan D.; Zhou, Xiaobo Eds, ISBN 978-0-7354-0466-3. | ||
8 | J. Fromentin, J.-P. Comet, P. Le Gall, O. Roux. Analysing Gene Regulatory Networks by both Constraint Programming and Model-Checking, EMBC'07, 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Lyon, France. August 23-26, 2007 pp. 4595-4598, 2007. | ||
7 | S. Troncale, J.-P. Comet, G. Bernot. Validation of biological models with Temporal Logic and Timed Hybrid Petri Nets, EMBC'07, 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Lyon, France. August 23-26, 2007 pp. 4603-4608, 2007. | ||
6 | M. Poudret, J.-P. Comet, P. Le Gall, A. Arnould, Ph. Meseure. Topology-based Geometric Modelling for Biological Cellular Processes, LATA 2007, first International Conference on Language and Automata Theory and Applications. Tarragona, Spain. March 29 - April 4, 2007 pp. 497-508, 2007. The proceedings are available on the website of the conference, Taux d'acceptation : 27.5%. | ||
5 | J. Ahmad, A. Richard, G. Bernot, J.-P. Comet, O. Roux. Delays in Biological Regulatory Networks, IWBRA 2006 / ICCS 2006: 6th International Conference. May 2006, LNCS. vol. 3992 pp. 887-894, 2006. Taux d'acceptation : 37%. | ||
4 | J.-P. Comet, H. Klaudel, S. Liauzu. Modeling multi-valued genetic regulatory networks using high-level Petri nets, ICATPN 2005. June 2005, LNCS. vol. 3536 pp. 208-227, 2005. | ||
3 | A. Richard, J.-P. Comet, G. Bernot. Graph-based Modeling of Biological Regulatory Networks : Introduction of Singular States, International workshop on Computational Methods in Systems Biology (CMSB). Paris, France. May 26-28, 2004, LNBI. vol. 3082 pp. 58-72, 2005. | ||
2 | G. Bernot, F. Cassez, J.-P. Comet, F. Delaplace, C. Müller, O. Roux, O. Roux. Semantics of Biological Regulatory Networks, BioConcur, Workshop on Concurrent Models in Molecular Biology. Marseille, France. 6 September, 2003, ENTCS, 2003. | ||
1 | S. Pérès, J.-P. Comet. Contribution of computational tree logic to biological regulatory networks: example from pseudomonas aeruginosa, International workshop on Computational Methods in Systems Biology (CMSB). Rovereto, Italy. February 24-26, 2003, LNCS. vol. 2602 pp. 47-56, 2003. Taux d'acceptation: 28 %. |
Refereed international conferences and workshops without proceedings (7)
Invited international conferences and workshops (9)
9 | G. Bernot, J.-P. Comet, O. Roux. A genetically modified Hoare logic that identifies the parameters of a gene network, 13th international Conference on Computational Methods in Systems Biology (CMSB 2015). Nantes, France. Sept. 16-18, 2015, LNBI. vol. 9308 pp. 8-12, 2015. | ||
8 | J.-P. Comet, G. Bernot. A Hoare logic for gene regulatory networks, 2nd Workshop on Computational Structural Biology: Integrative Approaches for Modeling Biomolecular Complexes. Nice, France. May 29-31, 2013, 2013. | ||
7 | G. Bernot, J.-P. Comet. On the use of temporal formal logic to model gene regulatory networks, 6th International Meeting on Computational Intelligence Methods for Bioinformatics and biostatistics (CIBB'2009). Eds. F. Masulli, L. Peterson, R. Tagliaferri. Genova, Italy. October 15th-17th 2009, LNBI. vol. 6160 pp. 112-138, 2009. | ||
6 | G. Bernot, J.-P. Comet, J. Guespin. A Discrete Approach to Model Biological Gene Regulatory Networks and the Use of Temporal Logic to Propose Wet Experiments, Gene regulatory networks: Dynamics, spatial organization and inference: Gennetec International Conference. Torino, Italy. April 23th-2th 2008, 2008. | ||
5 | G. Bernot, J.-P. Comet, J. Guespin. Using Formal Temporal Logic to Model Biological Regulatory Networks and to Propose New Wet Experiments, Genetics meets Systems Biology: Theory and Practice. Paris. November 13-15, 2006, 2006. Abstract in Proc. of SGF annual meeting, p.17. | ||
4 | G. Bernot, J.-P. Comet, J. Guespin. Formal methods from computer science to treat temporal properties of biological regulatory networks, applied to mucus production in Pseudomonas aeruginosa, Symposium "Modeling approaches in Systems Biology, Physiology, and Pathophysiology", 4th World Congress of Cell and Molecular Biology. Poitiers (Futuroscope). October 7-12, 2005, 2005. | ||
3 | M. Dutreix, J.-P. Comet, A. Cornuéjols, C. Froidevaux. Determination of cellular drug targets: Searching for functional informations in the jungle of microarrays data, Current Trends in Drug Discovery Research. India. Feb. 17-20, 2004, 2004. | ||
2 | P.P. Slonimski, M.-O. Mossé, P. Golik, A. Hénaut, Y. Diaz, J.-L. Risler, J.-P. Comet, J.-C. Aude, A. Wozniak, E. Glémet, J.-J. Codani. The first laws of genomics. , Microbial and Comparative Genomics in Microbial Genomes II: Sequencing, Functional Analysis and Comparative Genomics. January 31 - February 4, 1998. vol. 3 pp. 46, 1998. | ||
1 | P.P. Slonimski, J.-L. Risler, M.-O. Mossé, A. Hénaut, Y. Diaz, J.-P. Comet, J.-C. Aude, E. Glémet, J.-J. Codani. What can we learn about proteins from complete sequences of microbial genome, Protein Science. vol. 6 Suppl. 1, 1997. |
Invited national conferences and workshops (10)
10 | G. Bernot, J.-P. Comet. Towards a qualitative understanding of Cancer metabolism, Multidisciplinary Approaches in Cancer Research. Sophia Antipolis, France. 25-26 octobre, 2021. | ||
9 | J.-P. Comet. Automata, Logics and Biology, MOMI'2020. Sophia-Antipolis (France). 10 march, 2020. | ||
8 | J.-P. Comet, A. Richard, A. Muzy. Plasticité des réseaux de neurones: Un modèle de Réseaux Booléens avec règle de Hebb, Workshop sur la Théorie des réseaux booléens et ses applications en biologie. Nice, France. 4-7 novembre, 2014. | ||
7 | G. Bernot, J.-P. Comet, Z. Khalis, A. Richard, O. Roux. An extension of Hoare logic to identify the parameters of gene regulatory networks, Modélisation Mathématique des Systèmes Complexes, SMAI & SMF. Ecole Centrale Paris. 11-13 décembre, 2013. | ||
6 | F. Diener, A. Das, G. Bernot, J.-P. Comet, F. Eyssette. Correspondence between discrete and piecewise linear models of gene regulatory networks, actes du colloque à la mémoire d'Emmanuel Isambert, "Philosophie, méthodologie et applications de l'analyse non standard". Eds. A. Fruchard, V. Gautheron & T. Sari. Univ. Paris 7. 21-22 décembre, 2007. Publications de l'Université de Paris 13, pp. 185-194, 14 février 2012. | ||
5 | G. Bernot, J.-P. Comet, Z. Khalis. Une extension de la logique de Hoare pour les réseaux génétique, Rencontre scientifique : "Formalisme logique, apports et défis pour la modélisation de réseaux de régulation biologique". Rabat, Maroc. 12-15 avril, 2011. | ||
4 | G. Bernot, J.-P. Comet. Logique temporelle et Model-Checking pour les réseaux de régulation biologiques, 3ème Journées de Post-Génomique de la Doua (JPGD'03). Lyon, France. 14-16 mai, 2003. | ||
3 | J. Guespin-Michel, J.-P. Comet, G. Bernot. Comment valider un modèle mathématique en biologie?, AFADL'03. Rennes, France. 15-17 janvier, 2003. | ||
2 | G. Bernot, J. Michel-Guespin, A. Zemirline, J.-P. Comet, F. Delaplace, P. Ballet, P. Amar. Modélisation, observabilité et expérimentation : étude d'un cas, boucle de rétroaction positive dans un réseau de régulation génétique, Autran seminar (Isère). . 17-21 Mars, 2002. | ||
1 | J.-P. Comet, F. Tahi. Structuration et analyse des données d'expression de gènes, Journées Péri-Bio à l'université d'Evry. Evry, France. 25 avril, 2000. |
Refereed national conferences and workshops - with proceedings (2)
Refereed national conferences and workshops - without proceedings (8)
Other national conferences and workshops - without proceedings (5)
Miscellaneous ▲
Lectures at thematic schools (1)
1 | J.-P. Comet. Modélisation discrète et modélisation hybride de régulation génétique, Ecole Jeunes Chercheurs «Modélisation formelle de réseaux de régulation biologique», Ile de Porquerolles, 6-11 juin 2010. |
Posters (30)
30 | F. Camilleri, J. Wenda, A. Farhi, A. Bassignani, B. Kiehr, S. P. Tripathi, C. Buton, C. Pecoraro-Mercier, J.-P. Comet, E. Webb, D. Rouquie. Comparative Analysis of Acceptable Daily Intakes and Administered Equivalent Doses Derived from Cell Painting Points of Departure and Reverse Dosimetry, Abstracts of the 13th ASCCT Annual Meeting, Research Triangle Park, North Carolina (USA). Research Triangle Park, North Carolina (USA). 28-30 October 2024. | ||
29 | F. Camilleri, J. Wenda, A. Farhi, C. Buton, C. Pecoraro-Mercier, J.-P. Comet, D. Rouquié. Comparison of Acceptable Daily Intake (ADI) and in vivo doses extrapolated from in vitro point of departure obtained with cell painting on U2OS}, Abstracts of the 58th Congress of the European Societies of Toxicology (EUROTOX 2024), Copenhagen (Denmark). Copenhagen, Denmark. 8-11 September 2024. DOI https://doi.org/10.1016/j.tcs.2024.114505. | ||
28 | F. Camilleri, C. Ginet, V. Lejal, A. Bassignani, J.-P. Comet, D. Rouquié. Exploring cell morphological profile information for the de-risking of small molecules, JOBIM Poster session. Rennes, France. 5-8 july 2022. | ||
27 | L. Gibart, G. Bernot, J.-P. Comet, S. Vasseur. An abstract model of the metabolism regulation of pancratic ductal adenocarcinoma, JOBIM Poster session. Rennes, France. 5-8 july 2022. | ||
26 | L. Gibart, H. Collavizza, J.-P. Comet. Greening R. Thomas’ Framework: a Divide and Conquer, JOBIM Poster session. online, France. 6-9 july 2021. | ||
25 | D. Boyenval, G. Bernot, J.-P. Comet, F. Delaunay. Logical and incremental formalization of cell cycle checkpoints, JOBIM Poster session. online, France. 6-9 july 2021. | ||
24 | D. Boyenval, G. Bernot, H. Collavizza, J.-P. Comet. Introduction of Priority Regulation in Biological Regulatory Networks, Modelife annual Days. Cannes Mandelieu, France. 5-6 november 2019. | ||
23 | L. Gibart, G. Bernot, J.-P. Comet, F. Marchai-Guillaumond, S. Vasseur. Pancreas cancer modelling: a metabolic approach, 4ème École thématique de Modélisation Formelle de Réseaux de Régulation Biologique (France). Porquerolles, France. 23-28 juin 2019. | ||
22 | D. Boyenval, G. Bernot, J.-P. Comet, F. Delaunay. A discrete cell cycle model: from phases characterization toward observable properties verification, 4ème École thématique de Modélisation Formelle de Réseaux de Régulation Biologique (France). Porquerolles, France. 23-28 juin 2019. | ||
21 | U.D. Appadu, R. Khoodeeram, J.-P. Comet, G. Bernot, J.-Y. Trosset, V.S. Neergheen-Bhujun. Formal modelling of the impact of Pleurotus mushroom on energy metabolism in liver cancer, 4ème École thématique de Modélisation Formelle de Réseaux de Régulation Biologique (France). Porquerolles, France. 23-28 juin 2019. | ||
20 | I. Grenet, J.-P. Comet. How in vitro data can contribute to in vivo toxicity prediction using Machine Learning?, JOBIM, Marseille (France). Marseille (France). 3-6 juillet 2018. | ||
19 | I. Grenet, J.-P. Comet, F. Porée, D. Rouquié. Toward In Vivo Toxicity Prediction from Molecular Structures: A Two-Stage Machine Learning Approach, 57th Annual Meeting of Society of Toxicology (SoT). San Antonio (Texas), USA. 10-15 march 2018. | ||
18 | E. Cornillon, J.-P. Comet, G. Bernot, G. Enée. Hybrid Gene Networks: a new Framework and a Software Environment, 45ème congrès de la Société Francophone de Chronobiologie. Strasbourg. 14-16 septembre 2016. | ||
17 | B. Miraglio, G. Bernot, J.-P. Comet, C. Risso-de Faverney. Towards a Computer-Aided Toxycology, 3ème École thématique de Modélisation Formelle de Réseaux de Régulation Biologique. Porquerolles, France. 6-10 juin 2016. | ||
16 | E. Cornillon, J.-P. Comet, G. Bernot, G. Enée. Hybrid Gene Networks: a new Framework and a Software Environment, 3ème École thématique de Modélisation Formelle de Réseaux de Régulation Biologique. Porquerolles, France. 6-10 juin 2016. | ||
15 | J. Behaegel, J.-P. Comet, M. Folschette. A Hybridisation of the Genetically Modified Hoare Logic, 3ème École thématique de Modélisation Formelle de Réseaux de Régulation Biologique. Porquerolles, France. 6-10 juin 2016. | ||
14 | A. Das, F. Diener, G. Bernot, J.-P. Comet. Simplified model for the mammalian circadian clock, Thematic school on "Modelling complex biological systems in the context of genomics". Evry, France. 21-25 may 2012. | ||
13 | A. Das, F. Diener, G. Bernot, J.-P. Comet. Computational model for the mammalian circadian clock, Sophia-Antipolis, France. 23-27 may 2011. | ||
12 | Z. Khalis, G. Bernot, J.-P. Comet. Using Hoare logic for constraining parameters of discrete models of gene networks, JOBIM'2010. Montpellier. 7-9 septembre 2010. | ||
11 | Z. Khalis, G. Bernot, J.-P. Comet. Using Hoare logic for constraining parameters of discrete models of gene networks, Ecole thématique "Modélisation de systèmes biologiques complexes dans le contexte de la génomique". Evry. 3-7 mai 2010. | ||
10 | A. Das, F. Diener, G. Bernot, J.-P. Comet. Correspondence between discrete and continuous models of gene regulatory network, Ecole thématique "Modélisation de systèmes biologiques complexes dans le contexte de la génomique". Evry. 3-7 mai 2010. | ||
9 | J. Fromentin, J.-P. Comet, P. Le Gall, O. Roux. Analysing gene regulatory networks by both constraint programming and model-checking, Ecole thématique "Modélisation de systèmes biologiques complexes dans le contexte de la génomique". Evry. 30 avril - 4 mai 2007. | ||
8 | M. Poudret, J.-P. Comet, P. Le Gall, A. Arnould, P. Meseure. Topological Approach of the Golgi Apparatus: Towards a Discriminating Modelling ?, Ecole thématique "Modélisation de systèmes biologiques complexes dans le contexte de la génomique". Evry. 30 avril - 4 mai 2007. | ||
7 | D. Mateus, J.-P. Gallois, P. Le Gall, J.-P. Comet. Determining constraints in models of genetic regulatory networks using symbolic analysis, Jobim'2006. Bordeaux. 5-7 juillet, 2006. | ||
6 | J. Ahmad, A. Richard, G. Bernot, J.-P. Comet, O. Roux. Delays in Biological Regulatory networks, IPG'05. Lyon, France. December 1-2, 2005. | ||
5 | J.-P. Comet, P. Le Gall, G. Bernot. Qualitative Modelling of genetic networks: Extracting experiment schema from modelling, IPG'2004. Lyon, France. October 13-15, 2004. | ||
4 | J.-P. Comet, A. Richard. SMBioNet: a Tool for Modeling Biological Regulatory Networks Driven by Temporal Behavior, ECCB'03. Paris, France. September 27-30, 2003. | ||
3 | J.-P. Comet, S. Pérès, G. Bernot. CTL and biological regulatory networks : Example from P. Aeriginosa, Symposium on Macromolecular networks. Paris, France. July 8-12, 2002. | ||
2 | J.-P. Comet, S. Pérès, G. Bernot. Un langage formel pour les réseaux de régulation : un exemple avec multi-stationarité, Jobim'2002. Saint-Malo, France. 10-12 juin 2002. | ||
1 | J.-P. Comet. Extension of dynamic programming sequence alignment to pattern, WABI'2001. Arhus, Denmark. August 27-31, 2001. |
Research Reports (9)
Seminars (20)
20 | J.-P. Comet. some research activities around the modeling of complex biological networks. annual Sparks Day, Sophia-Antipolis (France), 24 septembre 2019. | ||
19 | J.-P. Comet, G. Bernot, E. Cornillon. Reductions symboliques de modèles de réseaux génétiques. Séminaire "Réseaux d’interactions: fondements et applications à la biologie", CIRM, Marseille (France), 3 janvier 2017. | ||
18 | J.-P. Comet, A. Richard, A. Muzy. Plasticité des neurones biologiques: un modèle de Réseaux Booléens avec règle de Hebb. Séminaire pour un groupe d'étudiants en visite à l'I3S, Nice (France), 6 janvier 2015. | ||
17 | J.-P. Comet. Introduction of time delays in formal models of gene regulatory networks. Séminaire, Impérial College, London, GB, 16 mai 2012. | ||
16 | G. Bernot, J.-P. Comet, J. Guespin. On the use of temporal formal logic to deduce the parameters of a gene regulatory network. Séminaire, Imperial College, London, GB, 16 mai, 2012. | ||
15 | J.-P. Comet. A Hoare Logic for discrete dynamical systems: application to gene networks. Séminaire, CI2MA, University of Concepción, Chili, 17 novembre 2011. | ||
14 | J.-P. Comet. Modélisation discrète et modélisation hybride de régulation génétique. séminaire du pôle MDSC, I3S, Université de Nice-Sophia, 23 juin 2010. | ||
13 | J.-P. Comet. Modélisation qualitative des Réseaux de régulation génétique. Séminaire BIOALGOME, Prism, UVSQ, 15 décembre 2005. | ||
12 | J.-P. Comet. Simulation qualitative des Réseaux de régulation biologique, modèle de H. de Jong. groupe de travail "Observabilité", génopole Evry, 24 novembre 2005. | ||
11 | J.-P. Comet, A. Richard, G. Bernot. Quelques problèmes autour de la modélisation des réseaux de régulation de R. Thomas. Séminaire, ENS Ulm, département informatique, Paris, 20 mai 2005. | ||
10 | J.-P. Comet. Représentation bipartie des réseaux de régulation biologique de R. Thomas. Séminaire du groupe de travail "Observabilité", génopole Evry, 27 janvier 2005. | ||
9 | J. Guespin, J.-P. Comet. Méthodes formelles appliquées aux réseaux de régulation de R. Thomas. Séminaire IGM, Orsay, France, 21 septembre 2004. | ||
8 | J.-P. Comet, G. Bernot. Logique temporelle et model-checking pour les réseaux de régulation biologique. Séminaire du groupe de travail "Observabilité", génopole Evry, 28 novembre 2002. | ||
7 | J.-P. Comet. Méthode de prédiction à partir des données transcriptionnelles: Combien de gènes témoins faut-il prendre en compte?. Séminaire du groupe de travail "Consensus", génopole Evry, 15 mai 2002. | ||
6 | J.-P. Comet. Recherche des gènes pouvant servir à la prédiction. Séminaire du groupe de travail "Consensus", génopole Evry, 7 mars 2002. | ||
5 | J.-P. Comet. Méthodes de prédiction à partir des données transcriptionnelles : Prise en compte des erreurs de mesure. Séminaire du groupe de travail "Consensus", génopole Evry, 11 avril 2001. | ||
4 | J.-P. Comet. Using error propagation for class prediction. Seminar, Whitehead Institute / MIT Center for Genome Research, Cambridge (MA), USA, November 1999. | ||
3 | J.-P. Comet. Chips quality and error bars. Seminar, Whitehead Institute / MIT Center for Genome Research, Cambridge (MA), USA, June 1999. | ||
2 | J.-P. Comet. Interprétation statistique du score Smith-Waterman. Un autre indice de similarité : le z-score. Séminaire du groupe "Statistique des Sequences Biologiques", INRA (Jouy-en-Josas, 78), octobre 1997. | ||
1 | J.-P. Comet. Analyse de données et Biologie moléculaire. Séminaire, LMCP, Jussieu (Paris), mars 1997. |